Set About: Begin a job, task.
They set about cleaning the house with great enthusiasm.

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Set Back: Cost.
The wedding set me back a huge amount of money.
 

Set Back: Cause delay, problems.
The weather set the building work back by two days.

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Set By: Use something to help you set a watch.
I always set my watch by Channel 2 news.

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Set Down: Allow passenger to leave vehicle.
The driver set me down just outside the house.

 

Set In: Come, likely to last a long time.
The snow has really set in now. We can't leave till tomorrow.

 

Set Off: Cause to explode.
The earthquake set off the old bomb.
 

Set Off: Leave on a journey.
We have to set off tomorrow very early.
 

Set Off: To make something more attractive by comparison.
Your dress really sets off your hair.

 

Set Up: Prepare.
They carefully set up the experiment.
 

Set Up: Start a business.
This company was set up in 1955.